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Descriptor English: Multiple Sclerosis
Descriptor Spanish: Esclerosis Múltiple
Descriptor esclerosis múltiple
Entry term(s) EM (esclerosis múltiple)
esclerosis diseminada
esclerosis múltiple aguda fulminante
Scope note: Enfermedad autoimmune que afecta principalmente a adultos jóvenes y caracterizada por destrucción de la mielina en el sistema nervioso central. Los hallazgos anatomopatológicos incluyen múltiples áreas bien definidas de desmielinización en toda la sustancia blanca del sistema nervioso central. Las manifestaciones clínicas incluyen ceguera, movimientos extraoculares anómalos, parestesias, pérdida de sensibilidad, decaimiento, disartria, espasticidad, ataxia, y disfunción de la vejiga. El patrón habitual está formado por ataques recurrentes seguidos de recuperación parcial (ver ESCLEROSIS MÚLTIPLE RECURRENTE-REMITENTE), pero también hay formas agudas fulminantes y progresivas crónicas (ver ESCLEROSIS MÚLTIPLE PROGRESIVA CRÓNICA). (Adams et al., Principles of Neurology, 6th ed, p903)
Descriptor Portuguese: Esclerose Múltipla
Descriptor French: Sclérose en plaques
Entry term(s): Disseminated Sclerosis
MS (Multiple Sclerosis)
Multiple Sclerosis, Acute Fulminating
Sclerosis, Disseminated
Sclerosis, Multiple
Tree number(s): C10.114.375.500
C10.314.350.500
C20.111.258.250.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009103
Scope note: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Related: Myelitis, Transverse MeSH
DeCS ID: 9296
Unique ID: D009103
NLM Classification: WL 360
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2010/06/25
Multiple Sclerosis - Preferred
Concept UI M0014197
Scope note An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Preferred term Multiple Sclerosis
Entry term(s) Disseminated Sclerosis
MS (Multiple Sclerosis)
Sclerosis, Disseminated
Sclerosis, Multiple
Multiple Sclerosis, Acute Fulminating - Narrower
Concept UI M0334267
Preferred term Multiple Sclerosis, Acute Fulminating



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